Detalhe da pesquisa
1.
Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain.
FASEB J
; 38(2): e23442, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38275103
2.
Cell-free protein production of a gamma secretase homolog.
Protein Expr Purif
; 215: 106407, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38000778
3.
Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state.
J Biol Chem
; 298(9): 102321, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921890
4.
Lipase-Catalyzed Production of Sorbitol Laurate in a "2-in-1" Deep Eutectic System: Factors Affecting the Synthesis and Scalability.
Molecules
; 26(9)2021 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34067126
5.
Macrocyclic Tetramers-Structural Investigation of Peptide-Peptoid Hybrids.
Molecules
; 26(15)2021 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361700
6.
The simulation of NMR data of flexible molecules: sagittamide A as an example for MD simulations with orientational constraints.
Phys Chem Chem Phys
; 22(30): 17375-17384, 2020 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32705098
7.
Urinary NMR Profiling in Pediatric Acute Kidney Injury-A Pilot Study.
Int J Mol Sci
; 21(4)2020 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32054020
8.
Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage.
Biophys J
; 116(11): 2103-2120, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31130234
9.
Structure of the membrane anchor of pestivirus glycoprotein E(rns), a long tilted amphipathic helix.
PLoS Pathog
; 10(2): e1003973, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24586172
10.
Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.
J Biol Chem
; 289(13): 8839-51, 2014 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24523409
11.
Autoinduced catalysis and inverse equilibrium isotope effect in the frustrated Lewis pair catalyzed hydrogenation of imines.
Chemistry
; 21(22): 8056-9, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25877865
12.
Dendrimer-type peptoid-decorated hexaphenylxylenes and tetraphenylmethanes: synthesis and structure in solution and in the gas phase.
Chemistry
; 20(49): 16273-8, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25297441
13.
Trehalose lipid biosurfactants produced by the actinomycetes Tsukamurella spumae and T. pseudospumae.
Appl Microbiol Biotechnol
; 98(21): 8905-15, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25091045
14.
Substrate Selection Criteria in Regulated Intramembrane Proteolysis.
ACS Chem Neurosci
; 15(7): 1321-1334, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38525994
15.
Thio-2 inhibits key signaling pathways required for the development and progression of castration resistant prostate cancer.
Mol Cancer Ther
; 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38412481
16.
Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) ß transmembrane segment.
J Biol Chem
; 287(31): 26178-86, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22619173
17.
Structure analysis of the membrane-bound PhoD signal peptide of the Tat translocase shows an N-terminal amphiphilic helix.
Biochim Biophys Acta
; 1818(12): 3025-31, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22960285
18.
Structural characterization of a peptoid with lysine-like side chains and biological activity using NMR and computational methods.
Org Biomol Chem
; 11(4): 640-7, 2013 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23223799
19.
Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by γ-Secretase.
J Mol Biol
; 435(18): 168218, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37536392
20.
Rapid calculation of protein chemical shifts using bond polarization theory and its application to protein structure refinement.
Phys Chem Chem Phys
; 14(35): 12263-76, 2012 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22868284